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Understanding influenza: Summary

  • Influenza or 'flu' is a highly infectious viral illness, spreading easily from person to person either through the air or through hand/face contact.
  • Annual outbreaks of 'ordinary' flu arise as a result of minor genetic changes in the flu viruses known as antigenic drift which produce different strains each year.
  • The more a flu strain differs from previously circulating strains, the less immunity a population will have to it.
  • 'Ordinary' flu epidemics kill between 500,000 and 1 million people worldwide every year; in the UK, they affect up to 10-15% of the population each year and cause around 12,000 deaths.
  • A pandemic flu virus is a novel flu virus to which the population has very little or no immunity.
  • Pandemic flu emerges as a result of major genetic changes in the flu virus known as antigenic shift and occurs roughly every 30 years.
  • Pandemic flu is generally associated with much higher rates of illness than 'ordinary' flu, affecting a quarter of the population or greater, and more deaths.
  • The worst flu pandemic last century killed around 40 million people worldwide and around 250,000 people in the UK alone.
  • For more information about flu and pandemic flu visit:

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