Six distinct phases have been defined by the World Health Organization to help global preparedness planning:
Inter-pandemic Period – new virus in animals, no human cases
Phase 1 Low risk of human cases
Phase 2 Higher risk of human cases
Pandemic Alert Period
Phase 3 No, or very limited, human-to-human transmission
Phase 4 Evidence of increased human-to-human transmission
Phase 5 Evidence of significant human-to-human transmission
Pandemic Period
Phase 6 Efficient and sustained human-to-human transmission
We are currently in Phase 3 as a virus new to humans is causing infections, but does not spread easily from one person to another.
Experts are concerned because the H5N1 virus currently circulating among birds in Africa, Asia and Europe has demonstrated the ability to cross the species barrier to cause disease and death in humans.
The World Health Organization (WHO) alert level remains at Phase 3 and a particular risk of pandemic emergence arises through adaption of the virus or recombination with circulating (human) viruses.
Although there have been no major changes in the behaviour of H5N1 viruses in humans or animals since they emerged a decade ago, it is possible that they could change suddenly. This could lead to more efficient transmission among humans.
The World Health Organization (WHO) continues to monitor the situation carefully.
When the international situation reaches WHO Phase 6 there will be 4 alert levels in the UK:
UK alert level 1 No cases in the UK
UK alert level 2 Virus isolated in the UK
UK alert level 3 Outbreak(s) in the UK
UK alert level 4 Widespread activity across the UK